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International Parkinson iyo Dhaqdhaqaaqa Xanuunka Bulshada

        Caddadka 29, ISSUE 3 • SEPTEMBER 2025. 

Qeexitaanka iyo kala soocida dystonia: Warbixin cusub oo la isku raacsan yahay  

Tan iyo markii la bilaabay in ka badan 100 sano ka hor,1 fikradda dystonia ayaa si weyn u kobcay. Muddo ka dib, waxaa jiray horumar ku saabsan sharraxaadaha qeexida astaamaha dystonia, oo ay weheliso kobaca noocyo badan oo cillado ah halkaas oo astaamaha dystonia laga soo sheegay.2-5 Warbixintii ugu horeysay ee caalami ah oo la isku raacsan yahay oo ku saabsan qeexida iyo kala soocida dystonia waxay soo muuqatay 2013, in ka badan 10 sano ka hor.6 Warbixintan, astaamo caafimaad oo badan oo kala duwan iyo sababaha ayaa loo kala saaray laba faasas, mid ka hadlaya astaamaha caafimaad, iyo tan kale oo wax ka qabanaysa sababaha noolaha. Warbixintani waxay si degdeg ah u noqotay halbeegga dahabiga ah, si weyna loo hirgeliyey. Habka laba dhidibka ah ee cusub ayaa markii dambe loo qaatay si loo kala saaro cilladaha dhaqdhaqaaqa kale, oo ay ku jiraan gariir7 iyo myoclonus.8   

Warbixinta la isku raacsan yahay ee 2013 waxay qiratay baahida suurtagalka ah ee isbeddelada mustaqbalka iyadoo wax badan laga bartay noocyada badan ee kala duwan ee dystonia. Toban sano ka dib markii la soo bandhigay, waxaa la dhisay guddi cusub oo dib u eegis ku sameeya dhaqangelinta soo jeedinta. Runtii, cilmi-baarisyo dhowr ah ayaa soo sheegay ku-dhaqanka kiliinikada ee lagu guuleystay ee qorshaha dadyow kala duwan, oo leh cillado yar.9-11 Intaa waxaa dheer, wax badan ayaa laga bartay dystonia, gaar ahaan ku saabsan kala duwanaanshaha bayooloji ee hoose. Laba sano oo dib u eegis ah kadib, warbixin la cusboonaysiiyay ayaa la sii daayay 2025 si wax looga qabto wixii la bartay kadib warbixintii asalka ahayd ee la isku afgartay.12   

Warbixinta cusubi waxay haysaa inta badan fikradaha warbixinta asalka ah, iyadoo badi isbeddelada ay ka tarjumayaan caddaynta ujeedada warbixinta asalka ah. Qeexida dystonia si weyn ayaa loo hayaa, marka laga reebo tixraacyada "muruqa murqaha" ayaa la tirtiray si looga hortago jahwareerka xanuunka neuromuscular.   

Waxaa jiray qaar ka mid ah caddaynta si ay u caawiyaan codsiga joogtada ah ee Axis I, iyo qaar ka mid ah sifooyin caafimaad oo dheeraad ah oo la xidhiidha noocyada hoose ee dystonia ayaa lagu daray. Waxyaabaha ugu muhiimsan ee lagu daro Axis Waxaan aqoonsanahay qaar ka mid ah astaamaha caafimaad ee la xiriira dystonia, sida xiriirka dhaqdhaqaaqa ikhtiyaariga ah iyo mararka qaarkood tayada gariir ama gariir.13 Guud ahaan, Axis I waxay bixisaa sharraxaad aad u dhammaystiran oo ku saabsan sifooyin caafimaad oo kala duwan oo khuseeya mahadnaqa kooxo-hoosaadyada gaarka ah ee dystonia.   

Qaar ka mid ah isbeddellada la taaban karo ayaa lagu sameeyay Axis II, sababtoo ah wax badan oo la bartay tobankii sano ee la soo dhaafay waxay la xiriiraan etiology iyo pathogenesis ee dystonia.14 Eray bixinta Axis II iyo qaab dhismeedkeeda ayaa dib loo eegay. Marka lagu daro qaar ka mid ah caddaynta erey-bixinta, Axis II hadda waxay si cad u aqoonsanaysaa kala duwanaanshaha bayooloji ee hoose ee noocyo badan oo dystonia ah. Inkasta oo kiisas badan ay ku sii jiraan qaybta "idiopathic", waxaa jiray koboc aad u weyn oo lagu qadarinayo kala duwanaanshaha etiologies iyo hababka bayooloji ee laga yaabo inay noqdaan korriin, hoos u dhac, dheef-shiid kiimikaad, difaaca jirka, ama kuwa kale.

Waxaan rajeyneynaa in warbixinta cusub ee la isku raacsan yahay ay fududeyn doonto ogaanshaha, daaweynta, iyo fahamka dheeraadka ah ee etiologies iyo hababka la wadaago ee dhammaan noocyada dystonia. Shaki la'aan, waxaa jiri doona baahi loo qabo cusbooneysiin dheeraad ah mustaqbalka, maadaama aan sii wadeyno inaan wax badan ka barano dystonia si xawli ah. 

Akhri warqadda

 

xigashooyinka 

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