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International Parkinson iyo Dhaqdhaqaaqa Xanuunka Bulshada

        Caddadka 30, ISSUE 1 • Maarso 2026.  Arrin buuxa

Yaanyada iyo cudurka Parkinson: Male-awaal hore oo dib loo eegay

Sannadkii 1989, Jacob Sage wuxuu soo jeediyay in yaanyada ay gacan ka geysan karto sababta cudurka Parkinson (PD) [1]. Waqtigaas, mala-awaalkiisu wuxuu inta badan u adeegay sidii tusaale kicin ah oo afka ah oo ku saabsan caqabadaha lagu aqoonsanayo sababaha PD. Warqaddayada 2], waxaan ka wada hadlaynaa sababta mala-awaalkan uu uga fogaa sidii markii hore loo malaynayay.

Gaar ahaan, caddaymaha isku xiraya soo-gaadhista sunta cayayaanka iyo asalka PD ayaa si xawli ah u kordhaya [3, 4]. Daraasado kala duwan oo ku saabsan cudurrada faafa ayaa helay xiriir ka dhexeeya PD iyo sunta cayayaanka qaarkood, taas oo ay sii taageerayaan daraasado ka hor kiliinikada [5-7]. In kasta oo daraasadaha badankood ay diiradda saareen soo-gaadhista shaqada, haddana caddaymaha soo baxaya waxay muujinayaan in dadka ku nool meel u dhow beeraha ama cuna waxyaabaha lagu daweeyay sunta cayayaanka ay sidoo kale la kulmi karaan khataro [8, 9].

Waxaa xiiso leh, ugu yaraan qaar ka mid ah cayayaankaas isla midka ah ayaa loo isticmaalaa beerista yaanyada. Si aan u helno aragti ku saabsan astaanta sunta cayayaanka ee loo isticmaalo wax soo saarka yaanyada, waxaan falanqeynay xogta isticmaalka sunta cayayaanka ee California - oo ah xaalad weyn oo yaanyo soo saarta [10]. Waxaan ogaanay in sunta cayayaanka ee ugu badan ee loo isticmaalo yaanyada ay hore ugu xirnaayeen PD (Jadwalka 1). Intaa waxaa dheer, tirada sii kordheysa ee sunta cayayaanka ee la isticmaalay sannado badan waxay kicineysaa walaac ku saabsan sunta neerfaha ee isku dhafan ama xitaa isku-dhafka ah, halkaas oo saameynta isku-dhafka ah ee sunta cayayaanka badan ay kordhin karto sunta neerfaha [11, 12]. Intaa waxaa dheer, waddamada leh kobaca ugu sarreeya ee beerista yaanyada, oo ay ku jiraan Shiinaha, Hindiya, iyo Mareykanka, ayaa sidoo kale leh baahsanaanta PD oo sii kordheysa, taasoo soo jeedinaysa in yaanyada wasakhaysan ay gacan ka geysan karto kobaca adduunka oo dhan ee PD.

Waxaan si buuxda u qireynaa in caddaymaha lagu soo bandhigay warqaddeenna ay yihiin kuwo xaaladeed iyo in mala-awaalkeennu uu weli yahay mid mala-awaal ah. In kasta oo aynaan sheegan in yaanyada - ama gaar ahaan sunta cayayaanka ee loo isticmaalo - ay yihiin sabab dhab ah oo keenta PD, waxaan aaminsanahay in isticmaalka sii kordhaya ee sunta cayayaanka ee beeraha iyo saameyntooda sunta neerfaha ee suurtagalka ah (wadarta) ay mudan yihiin tixgelin dhab ah. Waa muhiim in si taxaddar leh loo eego xeerarka sunta cayayaanka ee hadda jira iyo qiimeynta khatarta, kuwaas oo inta badan aan tixgelin saamaynta sunta neerfaha ee muddada dheer ee isku-dhafka shaqsiga ah, iyo gaar ahaan saameynta isku-dhafka ah ee isku-dhafka badan [13]. Cilmi-baarista mustaqbalka waa inay diiradda saartaa soo-gaadhista adduunka dhabta ah, oo ay ku jiraan qiimeyn khatar oo ku filan, iyadoo si gaar ah diiradda loo saarayo isdhexgalka ka dhexeeya soo-gaadhista deegaanka, oo ay ku jiraan suurtagalnimada sunta isku-darka iyo tan isku-dhafka ah. Natiijooyinka waxay gacan ka geysan karaan in la ogaado tallaabooyinka ka hortagga ee aadka loogu baahan yahay si loo yareeyo culeyska sii kordhaya ee PD adduunka oo dhan.

Jadwalka 1: Cayayaanka ugu sareeya ee lagu daweeyay yaanyada California oo dhan iyadoo la isticmaalayo rodol (2010-2020).

sunta Ku xiran PD [14–20] Fasalka kiimikada Qaabka ficilka
Trifluralin Haa Dinitroaniline Nidaam aan nidaamsanayn
Metam-sodium Haa Dithiocarbamate Nidaam aan nidaamsanayn
Chlorothalonil Haa Udgoon Polychlorine ah Nidaam aan nidaamsanayn
Sulfur Haa Kalkogen Nidaam aan nidaamsanayn
Glyphosate, cusbo isopropylamine ah Haa Phosphonoglycine Qaabdhismeed
Glyphosate, cusbo potassium ah   Phosphonoglycine Qaabdhismeed
Kaolin   Aluminosilicate Nidaam aan nidaamsanayn
Potassium N-methyldithiocarbamate   Dithiocarbamate Nidaam aan nidaamsanayn
S-metolachlor   Chloroacetanilide Qaabdhismeed
Chloroprikrin Haa Halonitroalkane Qaabdhismeed
1,3-Dichloropropene Haa Organochlorine Nidaam aan nidaamsanayn
Metolachlor   Chloroacetanilide Qaabdhismeed
Imidacloprid   Neonicotinoid Qaabdhismeed
Mancozeb Haa Dithiocarbamate Nidaam aan nidaamsanayn
Carbaryl Haa Carbamate Nidaam aan nidaamsanayn
Naxaas hydroxide Haa Xarunta Inorganic Nidaam aan nidaamsanayn
Dimethoate Haa Organophosphate Qaabdhismeed
Pendimethalin Haa Dinitroaniline Nidaam aan nidaamsanayn
Methyl bromide Haa Organobromine Qaabdhismeed
Diazinon Haa Organophosphate Qaabdhismeed
Ethephon ah Haa Organophosphate Qaabdhismeed
Chlorine   halogeen Nidaam aan nidaamsanayn

Cayayaanka ugu sareeya ee loo isticmaalo yaanyada marka la barbar dhigo wadarta guud ee maaddooyinka firfircoon ayaa la isticmaalaa sannad kasta laga bilaabo 2010 ilaa 2020. Isha: Xogta Warbixinta Isticmaalka Cayayaanka ee California (PUR) [10]. Cayayaan kasta oo cayayaan dila, waxaa lagu tilmaamaa in hore loogu xiriiriyay cudurka Parkinson (PD), iyo sidoo kale nooca kiimikada iyo inuu yahay mid nidaamsan ama aan nidaamsanayn.

 

tixraacyada 

  1. Sage JI. Yaanyada iyo cudurka Parkinson. Male-awaalka Caafimaadka. 1989;28(2):75-9. 
  2. Bogers JS, Paul KC, Dorsey ER, Bloem BR. Yaanyada iyo cudurka Parkinson - mala-awaal hore oo dib loo eegay. Mabaadi'da Caafimaadka. 2026;206. 
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  10. Waaxda California ee sharciyeynta cayayaanka (CDPR). Xogta Warbixinta Isticmaalka Cayayaanka (PUR) Waxaa laga heli karaa: https://www.cdpr.ca.gov/pesticide-use-in-california/. 
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  19. Narayan S, Liew Z, Paul K, Lee PC, Sinsheimer JS, Bronstein JM, iwm. Isticmaalka sunta cayayaanka ee organophosphorus ee guriga iyo cudurka Parkinson. Int J Epidemiol. 2013;42(5):1476-85. 
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